Technical Note:
l. The NOYORI catalysts are a ruthenium-based system containing a phosphine and 1,2-diamine ligand. The catalysts are used n the highlyefficient, enantio and diastereoselective hydrogenation of simple ketones. usually under the mild conditions of room temperature and 1-10 atm of hydrogen pressure.
References:
References: 1. J. Org. Chem., 1996, 61.4872. 2.Angew. Chem. Int. Ed., 2001, 40, 40 (review article). 3.J. Ám. Chem. Soc.. 1998, 120, 13529. 4.Angew. Chem Int. Ed., 1999.38. 495.Strem