Technical Notes:
1. Biaryl bisphosphine ligand with narrow dihedral angle. The DM-SEGPHOS ligand, as the ruthenium complex, gives superior
enantioselectivity and diastereoselectivity in the asymmetric hydrogenation of a-substituted-ß-ketoesters. See 15-0066
2. Ruthenium catalyzed enantioselective synthesis of ß amino acids by hydrogenation.
References:
1. US. Pat 7626034
Strem