Technical Notes:

1. Ligands of this type are currently used industrially in the stereoselective synthesis of commercial products 1.2. These ferrocene based phosphine ligands have wide application in the stereoselective hydrogenation of substituted acetamidoacrylates, enol acetates, ß-ketoesters and simple alkenes.4-B

2.Useful as a ligand in Pd-catalyzed C-N bond-forming reactions.

3.Pd-catalyzed enantioselective alkylative desymmetrization of meso-succinic anhydrides .

4. Asymmetric hydrogenation of ketones and phos phinylketimines .

5.Michael addition of Grignard reagents to a,a-unsaturated esters and thioesters.

6.Boration of a,a-unsaturated esters and nitriles.

7.Reaction of aryl halides with ammonia.

8.Cu-catalyzed reduction of activated c=c bonds with PMHS.

9. Regio- and enantioselective hydroboration of vinyl arenes.

10. Rh-catalyzed asymmetric ring-opening reactions of oxabicyclic alkenes .

11.1,2-Migrations in Pd-catalyzed Negishi couplings with JosiPhos ligands.

12.Catalyst for the homodimerization of ketoketenes.

13.L igand for the Rh catalyzed synthesis of lactones.

14.L igand for the Cu-catalyzed synthesis of syn and antiẞ-amino alcohols.

15. L igand for Rh-catalyzed Asymmetric Hydrosilylation of Dehydroalanine