Technical Notes:
1. Ligands of this type are currently used industrially in the stereoselective synthesis of commercial products 1,2. These ferrocene based phosphine ligands have wide application in the stereoselective hydrogenation of substituted acetamidoacrylates, enol acetates, ß-ketoesters and simple alkenes
2. Pd-catalyzed, enantioselective, intramolecular a-substituted cyclic ketones: facile synthesis of functionalized chiral spirobicycles.
3.Asymmetric boron conjugate addition of a,ß-unsaturated carbonyl compounds catalyzed by CuOTf/Josiphos under non-alkaline conditions
4.Chiral amides via copper cata lyzed enantioselective conjugate additicon 5. Ruthenium-catalyzed enantioselective synthesis of ß-amino alcohols from 1,2-diols by "borrowing hydrogen". 6.Cobalt catalyzed asymmetric addition of silylacetylenes to 1, 1-disubstituted allenes. 7.L igand for Catalytic Asymmetric Synthesis of Phosphine Boronates . 8. Ligand for Enantioselective Synthesis of Allylboronates and Allylic Alcohols by Cu-Catalyzed 1 ,6-Boration.
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